On the bright side, there are some promising therapeutic approaches on the horizon. Gene therapy has shown promise in patients with Leber congenital amaurosis, a form of severe, recessively-inherited retinal degeneration. Mouse models of induced pluripotent stem (IPS) cells have demonstrated the feasibility of regenerating photoreceptor cells and/or retinal tissue. These may be on the horizon, but they’re still a long way off. At best, a distant glimmer of hope for the thousands of patients living with retinal disease.