The safest piercing guns are single-use guns. That means it’s only used on one customer and then thrown away. This decreases the risk of infection. Piercing guns with sterilized disposable cassettes are also acceptable. But they don’t promise the same level of protection that single-use piercing guns do. Don’t receive a piercing from a reusable piercing gun that does not have sterilized disposable cassettes. These types of piercing guns cannot be autoclaved. An autoclave is a sterilization machine that uses heat to sterilize all non-disposable piercing tools. It helps make sure all tools are clean before they touch your body.