Madonna has a large blended family brood of children who seem incredibly tight-knit thanks to her strict parenting. Yes, the star has had a complicated relationship with her only biological son, but she undeniably shares an extraordinarily close bond with her biological daughter. The pair seems like best friends and are constant collaborators. Strangely enough, Madge actually feels the most connected to one of her adoptive children rather than the ones she gave birth to herself.